The Red Sox, despite a late-game collapse, managed to secure a 7-5 victory over the Tigers in 10 innings at Comerica Park.
After building a comfortable 4-0 lead, Boston saw it evaporate in the bottom of the ninth, but rallied back in extra innings.
Ceddanne Rafaela, who had been struggling recently, hit a two-run homer in the 10th inning, followed by a solo home run from Jarren Duran to give the Red Sox the win.
This victory marks a positive start to a six-game road trip for the Red Sox, who are looking to improve their away record to maintain a playoff position.