Scientists have discovered a new way to treat aggressive forms of cancer by targeting small fragments of rogue DNA that help tumors grow and resist chemotherapy.
The study found that many hard-to-treat cancers contain loops of malignant genetic material that are crucial for their survival.
These DNA fragments, called ecDNA, drive cancer growth and resistance, making them a promising target for new drugs.
Researchers have identified a drug currently in early-stage trials that could selectively destroy cells containing ecDNA and prevent tumors from developing resistance.
